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CAS No.: 42110-65-6
Synonyms: Silymarin
Silymarin, a polyphenolic flavonoid extracted from the seeds of Silybum marianum or milk thistle, is used in the prevention and treatment of liver diseases and primary liver cancer.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01935817 | Liver Fibrosis | Phase 3 | Completed | - | Italy ... more >> Cannizzaro Hospital Catania, Sicily, Italy, 95125 Collapse << |
NCT01957319 | Work Ability ... more >>Depression Collapse << | Phase 3 | Completed | - | Italy ... more >> University of Catania, Cannizzaro Hospital Catania, Italy, 95125 Collapse << |
NCT02146118 | Carcinoma, Non-Small-Cell Lung | Phase 2 | Unknown | March 2016 | Korea, Republic of ... more >> Gosin University Gospel Hospital Recruiting Busan, Korea, Republic of, 602-702 Collapse << |
实验方案
技术信息
CAS号 | 42110-65-6 | 储存条件 |
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分子式 | C25H22O10 | 运输 | 蓝冰 | |
分子量 | 482.44 | 别名 | Silymarin |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01935817 | Liver Fibrosis | Phase 3 | Completed | - | Italy ... more >> Cannizzaro Hospital Catania, Sicily, Italy, 95125 Collapse << |
NCT01957319 | Work Ability ... more >>Depression Collapse << | Phase 3 | Completed | - | Italy ... more >> University of Catania, Cannizzaro Hospital Catania, Italy, 95125 Collapse << |
NCT02146118 | Carcinoma, Non-Small-Cell Lung | Phase 2 | Unknown | March 2016 | Korea, Republic of ... more >> Gosin University Gospel Hospital Recruiting Busan, Korea, Republic of, 602-702 Collapse << |
NCT03687073 | Smoking | Phase 1 | Recruiting | July 2019 | United States, Minnesota ... more >> Masonic Cancer Center at University of Minnesota Recruiting Minneapolis, Minnesota, United States, 55455 Contact: Hanna Vanderloo, RN, MSN Collapse << |
NCT03538327 | Hypertension | Phase 4 | Completed | - | - |
NCT01265563 | Diabetic Nephropathy ... more >> Proteinuria Oxidative Stress Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> South Texas Health Care System, San Antonio, TX San Antonio, Texas, United States, 78229 Collapse << |
NCT03577587 | Breast Milk Production ... more >> Human Milk Feeding Hypogalactia Preterm Infant Nutrition Collapse << | Not Applicable | Recruiting | December 2020 | Germany ... more >> Evangelic Waldkrankenhaus Spandau, Paul Gerhardt Diakonie Recruiting Berlin-Spandau, Germany, 13589 Contact: Antonia Nomayo, MD 0049 30 3702 ext 2025 antonia.nomayo@pgdiakonie.de Contact: Frank Jochum, MD 0049 30 3702 ext 1022 frank.jochum@pgdiakonie.de Sub-Investigator: Antonia Nomayo, MD Sub-Investigator: Hanna Petersen, MD Sub-Investigator: Titus Sabi, MD Collapse << |
NCT02369536 | Non-alcoholic Fatty Liver Dise... more >>ase Collapse << | Not Applicable | Completed | - | Italy ... more >> IRCCS Neuromed Pozzilli, Isernia, Italy, 86077 Collapse << |
NCT00055445 | Hepatitis C, Chronic | Phase 1 Phase 2 | Completed | - | United States, Washington ... more >> University of Washington Medical Center Seattle, Washington, United States, 98105 Collapse << |
NCT00915200 | Diabetic Nephropathies ... more >> Proteinuria Oxidative Stress Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> University of Texas Hlth Sci Ctr San Ant San Antonio, Texas, United States, 78229 Collapse << |
NCT01463592 | Hepatitis C, Chronic | Phase 3 | Unknown | December 2013 | Pakistan ... more >> Medical Unit 1,Lahore General Hospital,Postgraduate Medical Institute Lahore, Punjab, Pakistan, 42200 Collapse << |
NCT01816490 | HIV Hepatitis... more >> C Collapse << | Phase 2 | Completed | - | Switzerland ... more >> Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich Zurich, Switzerland, 8091 Collapse << |
NCT00487721 | Prostate Cancer | Phase 2 | Completed | - | United States, Colorado ... more >> University of Colorado Hospital Aurora, Colorado, United States, 80010 Collapse << |
NCT01265563 | - | - | Completed | - | - |
NCT00200798 | - | - | Completed | - | United States, South Carolina ... more >> Medical University of South Carolina, GCRC Charleston, South Carolina, United States, 29425 Collapse << |
NCT01511523 | Non Alcoholic Fatty Liver Dise... more >>ase Collapse << | Not Applicable | Unknown | October 2012 | United States, North Carolina ... more >> Cumberland Research Associates, LLC Fayetteville, North Carolina, United States, 28304 Collapse << |
NCT00684268 | Hepatitis C | Phase 2 | Completed | - | Austria ... more >> Medical University of Vienna Wien, Austria, A1090 Collapse << |
NCT01402648 | Adenocarcinoma of Colon Recurr... more >>ent Collapse << | Phase 1 Phase 2 | Completed | - | Italy ... more >> Ospedale Policlinico Consorziale - Gastroenterology Unit Bari, Italy, 70124 Collapse << |
NCT03547895 | Decompensated Cirrhosis | Not Applicable | Completed | - | - |
NCT00065741 | HIV Seronegativity | Phase 1 | Completed | - | United States, North Carolina ... more >> General Clinical Research Center, Univiversity Of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599 Collapse << |
NCT00011635 | HIV Infection ... more >> Healthy Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> Warren G. Magnuson Clinical Center (CC) Bethesda, Maryland, United States, 20892 Collapse << |
NCT00487721 | - | - | Completed | - | - |
NCT03440164 | - | - | Completed | - | - |
NCT02633696 | Healthy Volunteers | Phase 1 | Completed | - | Spain ... more >> Hospital Ramón y Cajal Madrid, Spain, 28034 Collapse << |
NCT01871662 | Hepatitis C, Chronic | Phase 2 Phase 3 | Withdrawn | February 2016 | Egypt ... more >> Al-Manial University Hospital, Kasr El-Aini Faculty Medicine, Cairo University Cairo, Egypt Collapse << |
NCT02669641 | Fatty Liver | Phase 4 | Unknown | December 2016 | Romania ... more >> Research Center in Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania Recruiting Craiova, Please Select, Romania, 200349 Contact: Ioana Andreea Gheonea, Lecturer +40751268732 iagheonea@gmail.com Contact: Dan Ionut Gheonea, Assoc. Prof. +40751268731 digheonea@gmail.com Collapse << |
NCT02347319 | Chronic Liver Disease | Phase 4 | Completed | - | Korea, Republic of ... more >> The catholic university of korea, Bucheon ST. Mary's Hosipital Bucheon, Gyeonggi-do, Korea, Republic of, 420-717 Collapse << |
NCT02843451 | Body Dysmorphic Disorder | Phase 2 | Recruiting | October 2019 | United States, Illinois ... more >> University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Stephanie Valle, BA 773-834-1325 svalle@yoda.bsd.uchicago.edu Contact: Jon E Grant, JD, MD, MPH 7738341325 jongrant@uchicago.edu Collapse << |
NCT02337634 | Pathological Gambling ... more >> Gambling Disorder Collapse << | Phase 2 | Recruiting | October 2019 | United States, Illinois ... more >> University of Chicago Recruiting Chicago, Illinois, United States, 60637 Contact: Jon E Grant, JD, MD, MPH 773-834-3778 Principal Investigator: Jon E Grant, JD, MD, MPH Collapse << |
NCT02473913 | Trichotillomania ... more >> Hair Pulling Disorder Collapse << | Phase 2 | Active, not recruiting | June 2020 | United States, Illinois ... more >> University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
NCT01535092 | HCV Recurrence After Liver Tra... more >>nsplantation Collapse << | Phase 2 | Terminated(when realized that ... more >>the target 60% of patients with SVR was no more achievable) Collapse << | - | - |
NCT02878863 | Hepatitis, Autoimmune | Phase 3 | Withdrawn | July 2017 | China, Sichuan ... more >> West China Hospital Chengdu, Sichuan, China, 610041 Collapse << |
NCT00389376 | Hepatitis C N... more >>on-Alcoholic Fatty Liver Disease Collapse << | Phase 1 | Completed | - | United States, Massachusetts ... more >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, North Carolina The University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 University of Pittsburgh, Graduate School of Public Health Pittsburgh, Pennsylvania, United States, 15261 Collapse << |
NCT01003236 | Diabetic Nephropathy | Phase 2 | Completed | - | Iran, Islamic Republic of ... more >> Motahari Clinic Shiraz, Fars, Iran, Islamic Republic of, 71345 Collapse << |
NCT03659058 | Fibrosis, Liver | Not Applicable | Completed | - | - |
NCT00915681 | Amatoxin Poisoning ... more >> Amanita Poisoning Mushroom Poisoning Liver Failure Collapse << | Phase 2 Phase 3 | Recruiting | December 31, 2018 | United States, New Jersey ... more >> Recruitment Hot Line for the United States Recruiting Somerset, New Jersey, United States, 08873 Contact: Judy Sherry, BSN 866-520-4412 United States, Pennsylvania Mylan Recruiting Canonsburg, Pennsylvania, United States, 15317 Contact: Ketty Belizaire 908-566-8260 ketty.belizaire@mylan.com Contact: Gail Tribble 412-651-9530 gail.tribble@mylan.com Collapse << |
NCT00030030 | Hepatitis C, Chronic | Phase 2 | Completed | - | - |
NCT03174561 | Irritable Bowel Syndrome | Not Applicable | Recruiting | April 30, 2018 | Romania ... more >> Institute of Gastroenterology and Hepatology of Clinical Emergency Hospital "Sf. Spiridon" Recruiting Iasi, Romania Contact: Vasile L Drug, Lecturer vasidrug@email.com Collapse << |
NCT00412763 | Hepatitis | Phase 4 | Completed | - | - |
NCT00246363 | HIV Infections ... more >> Hepatitis C Collapse << | Phase 1 Phase 2 | Completed | - | United States, New York ... more >> Mount Sinai School of Medicine New York, New York, United States, 10029-6574 Collapse << |
NCT01001845 | Hemodialysis ... more >>End Stage Renal Disease Collapse << | Phase 2 | Completed | - | Iran, Islamic Republic of ... more >> Nemazi Hospital Shiraz, Fars, Iran, Islamic Republic of, 71345 Collapse << |
NCT00680342 | Chronic Hepatitis C | Phase 2 | Completed | - | United States, Massachusetts ... more >> Beth Israel Deaconess Medical Center Boston, Massachusetts, United States, 00215 United States, North Carolina University of North Carolina Chapel Hill, North Carolina, United States, 27599 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
NCT01091324 | Proteinuria | Phase 3 | Unknown | July 2010 | Taiwan ... more >> National Cheng-Kung University Hospital Taian, Taiwan Collapse << |
NCT00055718 | Drug/Agent Toxicity by Tissue/... more >>Organ Leukemia Collapse << | Phase 2 | Completed | - | United States, Florida ... more >> Miami Children's Hospital Miami, Florida, United States, 33155 United States, New York Winthrop University Hospital Mineola, New York, United States, 11501 Mount Sinai School of Medicine New York, New York, United States, 10029 Herbert Irving Comprehensive Cancer Center at Columbia University New York, New York, United States, 10032 United States, Ohio Children's Hospital Medical Center of Akron Akron, Ohio, United States, 44308-1062 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 United States, Washington Children's Hospital and Regional Medical Center - Seattle Seattle, Washington, United States, 98105-3916 Canada, Ontario McMaster Children's Hospital at Hamilton Health Sciences Hamilton, Ontario, Canada, L8N 3Z5 Collapse << |
NCT00999349 | Beta-thalassemia Major ... more >> Iron Overload Collapse << | Phase 2 Phase 3 | Unknown | - | Iran, Islamic Republic of ... more >> Isfahan University of Medical Sciences Isfahan, Iran, Islamic Republic of, 81744-176 Collapse << |
NCT01258686 | Hepatitis C | Phase 3 | Completed | - | Korea, Republic of ... more >> Byung Chul, Yoo Seoul, Korea, Republic of Collapse << |
NCT01049178 | Atopic Asthma | Phase 2 Phase 3 | Withdrawn(Lack of funding) | - | United States, Tennessee ... more >> Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232-2650 Collapse << |
NCT01518933 | Hepatitis C Virus Recurrence | Phase 2 | Terminated(when a blind review... more >> highlighted that at least 43% of patients had a virological response) Collapse << | - | Italy ... more >> Azienda Ospedaliero-Universitaria Policlinico Consorziale Bari, Italy, 70124 Collapse << |
NCT00680407 | Non-alcoholic Steatohepatitis | Phase 2 | Completed | - | United States, Massachusetts ... more >> Beth Isreal Deaconess Medical Center Boston, Massachusetts, United States, 02215 United States, North Carolina University of North Carolina - Chapel Hill Chapel Hill, North Carolina, United States, 27599 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 Thomas Jefferson University Philadelphia, Pennsylvania, United States, 19107 University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15213 United States, Texas Brooke Army Medical Center San Antonio, Texas, United States, 78234 Collapse << |
NCT02006498 | Non-alcoholic Fatty Liver Dise... more >>ase Collapse << | Phase 2 | Completed | - | Malaysia ... more >> University Malaya Medical Centre Kuala Lumpur, Federal Territory, Malaysia, 59100 Collapse << |
NCT00755950 | Acute Hepatitis A ... more >> Acute Hepatitis B Acute Hepatitis C Acute Hepatitis E Acute EBV Hepatitis Acute CMV Hepatitis Collapse << | Phase 2 Phase 3 | Terminated(Low enrollment) | - | Egypt ... more >> Alexandria University Hospital Alexandria, Alexandria Governorate, Egypt Tanta Fever Hospital Tanta, Gharbeya Governorate, Egypt Banha Fever Hospital Benha, Kaluobeya Governorate, Egypt Collapse << |
NCT01018615 | Chronic Hepatitis C ... more >> Oxidative Stress Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> University of North Carolina at Chapel Hill- UNC Health Care Chapel Hill, North Carolina, United States, 27514 Collapse << |
NCT03216668 | Liver Function Failure | Phase 3 | Recruiting | September 30, 2019 | Vietnam ... more >> Hue Central General Hospital Recruiting Hue, Vietnam Contact: Phuong Tran, BA. 84.72.3817 117 lienhe@nhatnhat.com Principal Investigator: Pham Nhu Hiep, Prof Sub-Investigator: Phan Thi Minh Huong, Dr. Collapse << |
NCT03130634 | Metastatic Colorectal Cancer | Phase 4 | Recruiting | July 2018 | Taiwan ... more >> Chung-Ho Memorial Hospital, Kaohsiung Medical University: Recruiting Kaohsiung, Taiwan, 807 Contact: Jaw-Yuan Wang, PhD cy614112@ms14.hinet.net Contact: Tsung-Kun Chang, MD tsungkunchang@gmail.com Principal Investigator: Jaw-Yuan Wang, Ph.D. Sub-Investigator: Tsung-Kun Chang, MD Collapse << |
NCT01752153 | Immune Abnormalities | Phase 1 | Completed | - | Iran, Islamic Republic of ... more >> Department of Immunology, School of Medicine, Shiraz University of Medical Sciences Shiraz, Fars, Iran, Islamic Republic of Collapse << |
NCT01829178 | Upper GI Cancer ... more >> Cisplatin Adverse Reaction Collapse << | Phase 2 Phase 3 | Completed | - | Iran, Islamic Republic of ... more >> Tehran University of Medical Science Tehran, Iran, Islamic Republic of Collapse << |
NCT01800487 | Tuberculosis | Not Applicable | Completed | - | Thailand ... more >> Gastroenterology and Hepatology, Ramathibodi hospital Bangkok, Thailand, 10400 Collapse << |
NCT00680407 | - | - | Completed | - | - |
NCT03749070 | Non-Alcoholic Fatty Liver Dise... more >>ase Collapse << | Not Applicable | Not yet recruiting | June 30, 2021 | - |
NCT01436929 | Tuberculosis | Not Applicable | Unknown | December 2013 | Korea, Republic of ... more >> Deog Kyeom Kim Recruiting Seoul, Korea, Republic of, 156-707 Contact: Deog Kyeom Kim, M.D. 82-2-870-2228 kimdkmd@gmail.com Sub-Investigator: Chang-Hoon Lee, M.D Sub-Investigator: Eun-young Heo, M.D. Sub-Investigator: Seo-Yoon Kim, M.D. Collapse << |
NCT02973295 | Non-Alcoholic Fatty Liver Dise... more >>ase Collapse << | Phase 4 | Not yet recruiting | June 30, 2019 | Croatia ... more >> Clinical Hospital Centre Rijeka, Kresimirova 42, Croatia, 51000 Collapse << |
NCT01292161 | Hepatitis C | Phase 2 | Completed | - | Iran, Islamic Republic of ... more >> Al-zahra university hospital Isfahan, Iran, Islamic Republic of Collapse << |
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